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Yuanyuan (Rose) Li

Research Emphasis Dr. Li’s research is primarily focused on studying the interaction of epigenetic mechanisms and environmental factors such as bioactive dietary compounds in human diseases including cancer, obesity and aging utilizing transgenic mice as main animal models. Nutrition is believed to be an important environmental factor that is involved in regulation of gene expression

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Shiyou Chen

Research Emphasis: Dr. Chen has a broad research interest in vascular biology. He has been studying molecular mechanisms underlying the development of a number of vascular diseases including abdominal aortic aneurysm, atherosclerosis, hypertension, restenosis and vascular remodeling following vascular injury such as angioplasty, etc. His efforts have been largely directed to investigate vascular smooth muscle

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Robert Schnabel

Research interests Molecular Biochemistry, bioinformatics Selected publications Taylor JF, Schnabel RD, Sutovsky P. Genomics of bull fertility. Animal. 2018 Jun;12(s1):s172-s183. doi: 10.1017/S1751731118000599. Bouwman AC, et al. Meta-analysis of genome-wide association studies for cattle stature identifies common genes that regulate body size in mammals. Nat Genet. 2018 Mar;50(3):362-367. doi: 10.1038/s41588-018-0056-5. Smith JL, Wilson ML, Nilson SM,

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Gary Weisman

Research interest Nucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease. Research description Nucleotide receptors (P2 receptors) are present in nearly all cells and tissues where they mediate diverse functions including the regulation of platelet aggregation, muscle contraction, neurotransmission, insulin secretion, epithelial ion transport, wound healing and cell growth. We have isolated the

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Leslie A. Lyons

Research interest The overall goal of the laboratory is to bring Precision / Genomic Medicine to Companion Animals to improve health of animals and humans. Research focuses on genetic aspects of domestic cats, including inherited diseases as biomedical models for humans, cat phenotypic and morphological traits and cat population dynamics, which are implied to genetic

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Jeffrey N. Bryan

Research interests Dr. Bryan’s research focuses on comparative examination of cancers in companion animals to better understand cancers in all species. Bryan is an associate professor of veterinary oncology and director of the Comparative Oncology and Epigenetics Laboratory. His particular areas of interest are targeted imaging and therapy and epigenetics of cancer. Targeted imaging and

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James M. Amos-Landgraf

Research Emphasis: Our laboratory studies human colon cancer through the use of animal models. Using genetically engineered models of colon cancer in the mouse rat and pig, we are better able to understand the molecular genetic events that influence the initiation and progression of cancer.  To help us understand human colon cancer development and discover potential

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Christian Lorson

Fields of Interest Molecular Genetics Gene Therapy Education Ph.D. 1997, University of Missouri-Columbia B.A. 1991, Colorado College Research Statement Molecular basis of spinal muscular atrophy; RNA processing; gene therapy. Spinal muscular atrophy (SMA) is an autosomal recessive disorder that is the leading genetic cause of infantile death. SMA is the most common inherited motor neuron

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Gary S. Johnson

Research Emphasis Whole genome sequencing to identify the molecular genetic causes of heritable canine diseases Selected Publications  Farias FH, Zeng R, Johnson GS, Wininger FA, Taylor JF, Schnabel RD, McKay SD, Sanders DN, Lohi H, Seppälä EH, Wade CM, Lindblad-Toh K, O’Brien DP, Katz ML. (2011) A truncating mutation in ATP13A2 is responsible for adult-onset

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Craig L. Franklin

Research emphasis: The overall goal of our laboratory is to support the needs of the Mutant Mouse and Rat Resource and Research Centers and biomedical community by performing research to understand how differing complex microbiota modulate animal models of disease and developing means to manipulate microbiota to ensure reproducibility of models being distributed. The Mutant Mouse

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Elizabeth Bryda

Research Emphasis Our laboratory takes a comparative medicine approach to studying human disorders such as polycystic kidney disease and inflammatory bowel disease by using a variety of animal models from rodents to zebrafish. We are interested in characterizing disease-causing genes and their protein products in order to elucidate the molecular pathways in which these genes/proteins

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Martin L. Katz

Lab website link Research Interest Neurodegenerative diseases Education Ph.D. Marquette University, University of California, Santa Cruz Selected publications Ru Y, Corado C, Soon RK, Melton AC, Harris A, Yu GK, Pryer N, Sinclair JR, Katz ML, Ajayi T, Jacoby D, Russell CB, Chandriani S.  Neurofilament light is a treatment-responsive biomarker in CLN2 disease.  Annals of

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Habib Zaghouani

Fields of Interest Cellular Immunology Education Ph.D. 1987, University of Paris, France Research Statement T cells in Immunity and Autoimmunity. Four research projects that focus on the biology of T cells and their role in immunity and autoimmunity are being pursued in my laboratory. The first, concerns investigation of the mechanism by which myelin-reactive T

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Susan C. McKarns

Fields of Interest Cellular and Molecular Immunology Education Ph.D., 2001, Michigan State University Research Statement T Cell Tolerance, Autoimmunity, Epigenetics, and Regulation of T Cell Differentiation The goal of our laboratory is directed towards the prevention and treatment of human autoimmune disorders, inflammatory diseases, and cancer. TGF-b is a family of secreted proteins that have

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Dongsheng Duan

Home Department website Fields of Interest Gene Therapy Education Ph.D. 1997, University of Pennsylvania Research Statement Application of recombinant adeno-associated virus (rAAV) in gene therapy. Research Focus: Recombinant adeno-associated virus (rAAV) transduction biology Duchenne muscular dystrophy (DMD) gene therapy Duchenne cardiomyopathy Canine model of muscular dystrophy Free radical in muscle function and ageing. Research Funding:

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John Cannon

Fields of Interest: Signal transduction Molecular genetics Protein molecular dynamics Education: B.S. 1978, University of Illinois-Urbana Ph.D. 1983, University of Wisconsin-Madison Post-doc 1987, University of Pennsylvania Research Statement Protein phosphorylation is a well-studied post-translational modification that regulates many aspects of protein function. Dr. Cannon uses a combination of powerful yeast molecular genetic techniques and computer

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Change Tan

Research summary Mechanism of incomplete cytokinesis during germ cell development Research description Novel means of generating conditional mutations The functions of genes predicted from genome sequencing projects must be identified. This relies greatly on the analysis of loss-of-function phenotypes. Conventional gene-targeting techniques generate loss-of-function mutations by permanently deleting the specific gene of interest or by

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Michael Garcia

Research summary Molecular and cellular control of nerve development and disease Research description Specification of axonal diameter is a key component of motor system development and functioning, as axonal diameter is major axonal property that specifies the velocity of electrical signal conduction in the nervous system. The diameter of myelinated axonal segments (internodes) is increased

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Pamela Brown

Research summary Molecular basis for polar growth in Agrobacterium tumefaciens Research description POSITIONS AVAILABLE: Postdoctoral scholar, graduate student, laboratory technician, and undergraduate student positions available now. Email resume to brownpb@missouri.edu My lab is interested in understanding the principles that govern bacterial morphology, a readily observable facet of microbial cell biology. One of the major unsolved

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Charlotte L. Phillips

Educational background Degree School Location Major BS University of Central Florida Orlando, Fla. Biology PhD North Carolina State University Raleigh, N.C. Biochemistry Notable honors and service Induction into the CAFNR Teaching Academy, 2008 William T. Kemper Fellowship for Teaching Excellence, 2004 Excellence in Education: Pre-Clinical, Medical Student Affairs Council, 2003 Best PBL Tutor, Block 6

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