To The Top
Guangfu Li

Research Emphasis: Dr. Guangfu Li is studying liver fibrosis, liver cancer, pancreatic cancer and lung cancer. Using cells, animal models and human biopsies, Dr. Li focuses on elucidating the underlying mechanisms mediating fibrosis, tumor growth and metastasis and tumor-induced immune tolerance. Based on the findings, Dr. Li aims to develop effective molecularly targeted diagnosis, molecularly targeted

Read More
Habib Zaghouani

Fields of Interest Cellular Immunology Education Ph.D. 1987, University of Paris, France Research Statement T cells in Immunity and Autoimmunity. Four research projects that focus on the biology of T cells and their role in immunity and autoimmunity are being pursued in my laboratory. The first, concerns investigation of the mechanism by which myelin-reactive T

Read More
David Pintel

Fields of Interest Molecular Virology Education Ph.D. 1979, University of Illinois Research Statement The parvoviruses are amongst the smallest of all viruses; they have a compact and highly regulated small (5kb) single-stranded DNA genome and thus provide an excellent opportunity for understanding the life cycle of an important pathogen at a detailed molecular level, with

Read More
Susan C. McKarns

Fields of Interest Cellular and Molecular Immunology Education Ph.D., 2001, Michigan State University Research Statement T Cell Tolerance, Autoimmunity, Epigenetics, and Regulation of T Cell Differentiation The goal of our laboratory is directed towards the prevention and treatment of human autoimmune disorders, inflammatory diseases, and cancer. TGF-b is a family of secreted proteins that have

Read More
Dongsheng Duan

Home Department website Fields of Interest Gene Therapy Education Ph.D. 1997, University of Pennsylvania Research Statement Application of recombinant adeno-associated virus (rAAV) in gene therapy. Research Focus: Recombinant adeno-associated virus (rAAV) transduction biology Duchenne muscular dystrophy (DMD) gene therapy Duchenne cardiomyopathy Canine model of muscular dystrophy Free radical in muscle function and ageing. Research Funding:

Read More
John Cannon

Fields of Interest: Signal transduction Molecular genetics Protein molecular dynamics Education: B.S. 1978, University of Illinois-Urbana Ph.D. 1983, University of Wisconsin-Madison Post-doc 1987, University of Pennsylvania Research Statement Genetics of Saccharomyces cerevisiae; Role of protein phosphatase in cell cycle regulation. Faithful transmission of the genome to progeny cells is a fundamental process required by all

Read More
Donald Burke

Fields of Interest Mechanism and evolution of catalysis by ribozymes. Education Ph.D. 1992, University of California, Berkeley Research Statement Understand the mechanism and evolution of catalysis by ribozymes and the molecular basis of retroviral inhibition by RNA-based drugs. Both aptamers and ribozymes are found in nature and can be isolated from combinatorial libraries containing ~1015

Read More
Michael J. Petris

Educational background Degree School Location Major BSc University of Melbourne Melbourne, Australia Biochemistry/Genetics PhD University of Melbourne Melbourne, Australia Genetics Notable honors and service Organizer FASEB Conference on Trace Element Micronutrients, 2006 Organizing Committee, 5th International Meeting on Copper Homeostasis and its Disorders, 2006 Scientific Advisory Committee, Gordon Research Conference on Cell Biology of Metals,

Read More