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Paul DeFigueiredo

Paul DeFigueiredo

01-30-24

Research Emphasis His lab actively pursues research into host mechanisms that control intracellular parasitism by viral, bacterial and fungal pathogens, including Brucella melitensis, the causative agent of one of the world’s most prevalent zoonotic diseases, and Cryptococcus neoformans, the world’s deadliest fungal pathogen. He also has significant interest in...

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Adam Schrum

Adam Schrum

10-27-21

Research Emphasis Our laboratory is focused on physiologic signaling networks and how they function in molecular and cellular immunity. A main goal is to increase understanding of how T cells of the immune system decide whether to destroy or tolerate healthy, infected or cancerous tissue, with an eye toward...

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Guangfu Li

Guangfu Li

12-16-19

Research Emphasis: Dr. Guangfu Li is studying liver fibrosis, liver cancer, pancreatic cancer and lung cancer. Using cells, animal models and human biopsies, Dr. Li focuses on elucidating the underlying mechanisms mediating fibrosis, tumor growth and metastasis and tumor-induced immune tolerance. Based on the findings, Dr. Li aims to develop...

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Habib Zaghouani

Habib Zaghouani

11-15-19

Fields of Interest Cellular Immunology Education Ph.D. 1987, University of Paris, France Research Statement T cells in Immunity and Autoimmunity. Four research projects that focus on the biology of T cells and their role in immunity and autoimmunity are being pursued in my laboratory. The first, concerns investigation of...

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Susan C. McKarns

Susan C. McKarns

11-15-19

Fields of Interest Cellular and Molecular Immunology Education Ph.D., 2001, Michigan State University Research Statement T Cell Tolerance, Autoimmunity, Epigenetics, and Regulation of T Cell Differentiation The goal of our laboratory is directed towards the prevention and treatment of human autoimmune disorders, inflammatory diseases, and cancer. TGF-b is a...

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Dongsheng Duan

Dongsheng Duan

11-15-19

Home Department website Fields of Interest Gene Therapy Education Ph.D. 1997, University of Pennsylvania Research Statement Application of recombinant adeno-associated virus (rAAV) in gene therapy. Research Focus: Recombinant adeno-associated virus (rAAV) transduction biology Duchenne muscular dystrophy (DMD) gene therapy Duchenne cardiomyopathy Canine model of muscular dystrophy Free radical in...

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John Cannon

John Cannon

11-15-19

Fields of Interest: Signal transduction Molecular genetics Protein molecular dynamics Education: B.S. 1978, University of Illinois-Urbana Ph.D. 1983, University of Wisconsin-Madison Post-doc 1987, University of Pennsylvania Research Statement Protein phosphorylation is a well-studied post-translational modification that regulates many aspects of protein function. Dr. Cannon uses a combination of powerful...

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Donald Burke

Donald Burke

11-15-19

Fields of Interest Mechanism and evolution of catalysis by ribozymes. Education Ph.D. 1992, University of California, Berkeley Research Statement Understand the mechanism and evolution of catalysis by ribozymes and the molecular basis of retroviral inhibition by RNA-based drugs. Both aptamers and ribozymes are found in nature and can be...

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Michael J. Petris

Michael J. Petris

11-15-19

Educational background Degree School Location Major BSc University of Melbourne Melbourne, Australia Biochemistry/Genetics PhD University of Melbourne Melbourne, Australia Genetics Notable honors and service Organizer FASEB Conference on Trace Element Micronutrients, 2006 Organizing Committee, 5th International Meeting on Copper Homeostasis and its Disorders, 2006 Scientific Advisory Committee, Gordon Research...

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