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Christian Lorson

Fields of Interest Molecular Genetics Gene Therapy Education Ph.D. 1997, University of Missouri-Columbia B.A. 1991, Colorado College Research Statement Molecular basis of spinal muscular atrophy; RNA processing; gene therapy. Spinal muscular atrophy (SMA) is an autosomal recessive disorder that is the leading genetic cause of infantile death. SMA is the most common inherited motor neuron

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David Pintel

Fields of Interest Molecular Virology Education Ph.D. 1979, University of Illinois Research Statement The parvoviruses are amongst the smallest of all viruses; they have a compact and highly regulated small (5kb) single-stranded DNA genome and thus provide an excellent opportunity for understanding the life cycle of an important pathogen at a detailed molecular level, with

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Donald Burke

Fields of Interest Mechanism and evolution of catalysis by ribozymes. Education Ph.D. 1992, University of California, Berkeley Research Statement Understand the mechanism and evolution of catalysis by ribozymes and the molecular basis of retroviral inhibition by RNA-based drugs. Both aptamers and ribozymes are found in nature and can be isolated from combinatorial libraries containing ~1015

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