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Craig L. Franklin

Research emphasis: The overall goal of our laboratory is to support the needs of the Mutant Mouse and Rat Resource and Research Centers and biomedical community by performing research to understand how differing complex microbiota modulate animal models of disease and developing means to manipulate microbiota to ensure reproducibility of models being distributed. The Mutant Mouse

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Elizabeth Bryda

Research Emphasis Our laboratory takes a comparative medicine approach to studying human disorders such as polycystic kidney disease and inflammatory bowel disease by using a variety of animal models from rodents to zebrafish. We are interested in characterizing disease-causing genes and their protein products in order to elucidate the molecular pathways in which these genes/proteins

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Change Tan

Research summary Mechanism of incomplete cytokinesis during germ cell development Research description Novel means of generating conditional mutations The functions of genes predicted from genome sequencing projects must be identified. This relies greatly on the analysis of loss-of-function phenotypes. Conventional gene-targeting techniques generate loss-of-function mutations by permanently deleting the specific gene of interest or by

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