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Guangfu Li

Research Emphasis: Dr. Guangfu Li is studying liver fibrosis, liver cancer, pancreatic cancer and lung cancer. Using cells, animal models and human biopsies, Dr. Li focuses on elucidating the underlying mechanisms mediating fibrosis, tumor growth and metastasis and tumor-induced immune tolerance. Based on the findings, Dr. Li aims to develop effective molecularly targeted diagnosis, molecularly targeted

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James M. Amos-Landgraf

Research Emphasis: Our laboratory studies human colon cancer through the use of animal models. Using genetically engineered models of colon cancer in the mouse rat and pig, we are better able to understand the molecular genetic events that influence the initiation and progression of cancer.  To help us understand human colon cancer development and discover potential

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Craig L. Franklin

Research emphasis: The overall goal of our laboratory is to support the needs of the Mutant Mouse and Rat Resource and Research Centers and biomedical community by performing research to understand how differing complex microbiota modulate animal models of disease and developing means to manipulate microbiota to ensure reproducibility of models being distributed. The Mutant Mouse

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Susan C. McKarns

Fields of Interest Cellular and Molecular Immunology Education Ph.D., 2001, Michigan State University Research Statement T Cell Tolerance, Autoimmunity, Epigenetics, and Regulation of T Cell Differentiation The goal of our laboratory is directed towards the prevention and treatment of human autoimmune disorders, inflammatory diseases, and cancer. TGF-b is a family of secreted proteins that have

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