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R. Michael Roberts

R. Michael Roberts

Animal Sciences,

Curators' Professor

robertsrm@missouri.edu

(573) 882-0908

Education

BA Botany Oxford University Oxford, England
PhD Plant Physiology/Biochemistry Oxford University Oxford, England

Research Area

Reproductive biology: signaling between conceptus and uterus; stem cells.

Selected publications:

Yuan Y, Park J, Tian Y, Choi J, Pasquariello R, Alexenko AP, Dai A, Behura SK, Roberts RM, Ezashi T. (2019). A six-inhibitor culture medium for improving naïve-type pluripotency of porcine pluripotent stem cells. Cell Death Discov. 5:104. doi: 10.1038/s41420-019-0184-4. eCollection 2019.

Sheridan MA, Yang Y, Jain A, Lyons AS, Yang P, Brahmasani SR, Dai A, Tian Y, Ellersieck MR, Tuteja G, Schust DJ, Schulz LC, Ezashi T, Roberts RM. (2019). Early onset preeclampsia in a model for human placental trophoblast. Proc Natl Acad Sci U S A. 2019 Feb 20. doi: 10.1073/pnas.1816150116.

Karvas RM, Yang Y, Ezashi T, Schust DJ, Roberts RM, Schulz LC. (2018). ITGA1 is upregulated in response to oxygen over time in a BMP4 model of trophoblast. Mol Reprod Dev. 85(8-9):738-739. doi: 10.1002/mrd.23047.

Sheridan MA, Balaraman V, Schust DJ, Ezashi T, Roberts RM, Franz AWE. (2018). African and Asian strains of Zika virus differ in their ability to infect and lyse primitive human placental trophoblast. PLoS One. 13(7):e0200086. doi: 10.1371/journal.pone.0200086. eCollection 2018.

Roberts RM, Ezashi T, Sheridan MA, Yang Y. (2018). Specification of trophoblast from embryonic stem cells exposed to BMP4. Biol Reprod. 99(1):212-224. doi: 10.1093/biolre/ioy070.

Bayer A, Lennemann NJ, Ouyang Y, Sadovsky E, Sheridan MA, Roberts RM, Coyne CB, Sadovsky Y. (2018). Chromosome 19 microRNAs exert antiviral activity independent from type III interferon signaling. Placenta. 61:33-38. doi: 10.1016/j.placenta.2017.11.004.

Jain A, Ezashi T, Roberts RM, Tuteja G. (2017). Deciphering transcriptional regulation in human embryonic stem cells specified towards a trophoblast fate. Sci Rep. 7(1):17257. doi: 10.1038/s41598-017-17614-5.

Roberts RM. (2017). 30 years on from the molecular cloning of interferon-tau. Reproduction. 154(5):E1-E2. doi: 10.1530/REP-17-0585.

Yuan Y, Spate LD, Redel BK, Tian Y, Zhou J, Prather RS, Roberts RM. (2017). Quadrupling efficiency in production of genetically modified pigs through improved oocyte maturation. Proc Natl Acad Sci U S A. 114(29):E5796-E5804. doi: 10.1073/pnas.1703998114.

Sheridan MA, Yunusov D, Balaraman V, Alexenko AP, Yabe S, Verjovski-Almeida S, Schust DJ, Franz AW, Sadovsky Y, Ezashi T, Roberts RM. (2017). Vulnerability of primitive human placental trophoblast to Zika virus. Proc Natl Acad Sci U S A. 114(9):E1587-E1596. doi: 10.1073/pnas.1616097114.

Genovese NJ, Domeier TL, Telugu BP, Roberts RM. (2017). Enhanced Development of Skeletal Myotubes from Porcine Induced Pluripotent Stem Cells. Sci Rep. 7:41833. doi: 10.1038/srep41833.