Research Areas for the Genetics Area Program

The University of Missouri-Columbia (MU) is one of only 31 public universities selected for membership in the Association of American Universities and is also designated a Research University I by the Carnegie Foundation.

MU provides first-class research facilities, which allow faculty and students to use equipment and other resources to maximize their research capability at a minimal cost. Newly renovated facilities and new buildings, such as the $60 million Life Sciences Center, provide students and faculty with access to modern labs and equipment.

Facilities administered by the Molecular Biology Program

  • Cell and Immunobiology Core provide custom monoclonal antibodies, flow cytometic analysis and tissue culture reagents.
  • DNA Core provides DNA sequencing, synthesis, genotyping and microarray services, maintains a freezer inventory program for molecular biology enzymes and reagents, provides support for computer analysis of nucleic acid and protein sequence data, and operates robotic instrumentation for high throughput plasmid isolation, colony picking and genomic library management.
  • Electron Microscopy Core is a resource center for scanning and transmission electron microscopy, providing investigators with consultation, training and services.
  • Molecular Cytology Core is a resource for all types of light microscopy, immunocytochemistry, in situ hybridization techniques and general scientific image processing.
  • Nuclear Magnetic Resonance Facility is used for structural elucidation and study of chemical and biological reactions.
  • Proteomics Center includes protein expression profiling, determination of protein interaction and complex formation and analysis of protein trafficking and subcellular compartmentation.
  • Transgenic Animal Core applies proven techniques to the germline modification of mice.
  • Structural Biology Core offers assistance in unraveling the three dimensional structure of biological molecules by providing technical expertise in protein purification and crystallization, and instrumentation for NMR Spectroscopy and X-ray diffraction analysis.

Other Campus Facilities

  • Research Reactor Center provides unique capabilities for both neutron beam research and irradiation facilities for producing a variety of isotopes and performing activation analysis. The central focus of this research center is a 10 MW light-water reactor that is the highest power university research reactor in the United States.
  • X-Ray Diffraction Facility allows for rapid data collection on crystals and determines structure of molecules.
  • Mass Spectrometry Facility provides structural elucidation by mass spectrometry with a capability of low-resolution, electron impact and chemical ionization.
  • Low-level Radiation Laboratory is capable of detecting minute amounts of naturally occurring isotopes in humans and animals. It includes a large, whole-body liquid scintillation counter.
  • Rat Resource and Research Center provides a variety of inbred, hybrid and genetically modified rats to researchers worldwide.

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Interdisciplinary Life Science Research Laboratories:

  • Plant
  • Microbe
  • Structural
  • Biomedical
  • Animal

The Genetics Area Program integrates cutting edge research from 13 different departments on campus. Some exciting research areas include the following:

  • Aging
  • Cancer
  • Development
  • Disease Resistance
  • Evolution
  • Genomics
  • Microbe Interactions
  • Plant Molecular Biology
  • Proteomics
  • Reproductive Biology
  • Viral Genetics

Nearly 60 life sciences faculty from departments such as:

  • Agronomy
  • Animal Sciences
  • Biochemistry
  • Biological Sciences
  • Chemistry
  • Internal Medicine
  • Nutritional Sciences
  • Molecular Microbiology & Immunology
  • Ophthalmology
  • Pathology & Anatomical Sciences
  • Plant Microbiology & Pathology
  • Physiology
  • Veterinary Pathobiology

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